Autoantibodies and diseases.

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Thyroid Autoantibodies and Autoimmune Diseases

Abnormalities in the thyroid function and thyroid autoantibodies have been frequently described in patients with autoimmune diseases but seldom in antiphospholipid syndrome patients. In order to determine the prevalence of thyroid function and autoimmune abnormalities, we compared serum thyrotropin (TSH, serum free thyroxine (T4) levels, thyroid antithyroglobulin (TgAb) and antithyroperoxidase ...

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CYP2E1 autoantibodies in liver diseases

Autoimmune reactions involving cytochrome P4502E1 (CYP2E1) are a feature of idiosyncratic liver injury induced by halogenated hydrocarbons and isoniazid, but are also detectable in about one third of the patients with advanced alcoholic liver disease (ALD) and chronic hepatitis C (CHC). In these latter the presence of anti-CYP2E1 auto-antibodies is an independent predictor of extensive necro-in...

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The role-playing autoantibodies in autoimmune thyroid diseases and their extra-thyroidal manifestations: review article

The presence of the antibodies against the main thyroid antigens, which include thyroid peroxidase (TPO) or microsomal antigen, thyroglobulin (Tg) as well as thyrotropin receptor or Thyroid Stimulating Hormone Receptor (TSH-R), is a hallmark and symbol of the autoimmune thyroid diseases (AITDs) as one of the most common autoimmune diseases (AD) around the world. The prevalence of the thyroid pe...

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Gastrointestinal-associated autoantibodies in different autoimmune diseases.

BACKGROUND Gastrointestinal (GI)-related autoantibodies (Abs) are rarely evaluated in autoimmune diseases (AID) other than inflammatory bowel disease, autoimmune hepatitis and celiac disease. Our aim was to determine the prevalence of these antibodies in a wide spectrum of AID. METHODS We examined 923 serum samples representing 18 AID and compared them with 338 samples from healthy subjects. ...

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Antiplectin autoantibodies in subepidermal blistering diseases.

BACKGROUND Hemidesmosomal proteins may become targets of autoimmunity in subepidermal blistering diseases. Well-known recognized autoantigens are the intracellular plaque protein BP230, the transmembrane BP180 and its shed ectodomain LAD-1. OBJECTIVES To establish the prevalence of autoimmunity against plectin, another intracellular plaque protein, and to investigate its antigenic sites. ME...

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ژورنال

عنوان ژورنال: Nihon Naika Gakkai Zasshi

سال: 1988

ISSN: 0021-5384,1883-2083

DOI: 10.2169/naika.77.1494